Zelkovamycin, a New Cyclic Peptide Antibiotic from Streptomyces sp. K96-0670 I. Production, Isolation and Biological Properties

HUA ZHANG; HIROSHI TOMODA; NORIKO TABATA; MASAKO OOHORI; MAYUMI SHINOSE; YOKO TAKAHASHI; SATOSHI OMURA

doi:10.7164/antibiotics.52.29

Zelkovamycin, a New Cyclic Peptide Antibiotic from Streptomyces sp. K96-0670

I. Production, Isolation and Biological Properties

HUA ZHANG, HIROSHI TOMODA, NORIKO TABATA, MASAKO OOHORI, MAYUMI SHINOSE, YOKO TAKAHASHI, SATOSHI OMURA

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JOURNAL FREE ACCESS

1999 Volume 52 Issue 1 Pages 29-33

DOI https://doi.org/10.7164/antibiotics.52.29

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Abstract

A new antibiotic termed zelkovamycin was isolated from the fermentation broth of Streptomyces sp. K96-0670 by solvent extraction, ODS column chromatography and preparative HPLC. Zelkovamycin showed antibacterial activity against Xanthomonas oryzae, Acholeplasma laidlawii, Pyricularia oryzae and Staphylococcus aureus.

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