Structure Elucidation of Fungal Beauveriolide III, a Novel Inhibitor of Lipid Droplet Formation in Mouse Macrophages

ICHIJI NAMATAME; HIROSHI TOMODA; NORIKO TABATA; SHUYI SI; SATOSHI OMURA

doi:10.7164/antibiotics.52.7

ICHIJI NAMATAME, HIROSHI TOMODA, NORIKO TABATA, SHUYI SI, SATOSHI OMURA

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JOURNAL FREE ACCESS

1999 Volume 52 Issue 1 Pages 7-12

DOI https://doi.org/10.7164/antibiotics.52.7

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Abstract

The structure of fungal beauveriolide III, an inhibitor of lipid droplet formation in mouse macrophages, was elucidated to be cyclo-[(3S, 4S)-3-hydroxy-4-methyloctanoyl-Lphenylalanyl-L-alanyl-D-allo-isoleucyl] by spectral analyses and chemical degradation.

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