Haematocin, a New Antifungal Diketopiperazine Produced by Nectria haematococca Berk, et Br. (880701a-l) Causing Nectria Blight Disease on Ornamental Plants

YOSHIKATSU SUZUKI; HIROSHI TAKAHASHI; YASUAKI ESUMI; TSUTOMU ARIE; TETSUICHIRO MORITA; HIROYUKI KOSHINO; JUN UZAWA; MASAKAZU URAMOTO; ISAMU YAMAGUCHI

doi:10.7164/antibiotics.53.45

YOSHIKATSU SUZUKI, HIROSHI TAKAHASHI, YASUAKI ESUMI, TSUTOMU ARIE, TETSUICHIRO MORITA, HIROYUKI KOSHINO, JUN UZAWA, MASAKAZU URAMOTO, ISAMU YAMAGUCHI

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JOURNAL FREE ACCESS

2000 Volume 53 Issue 1 Pages 45-49

DOI https://doi.org/10.7164/antibiotics.53.45

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Abstract

A new antifungal diketopiperazine named haematocin was isolated from the culture broth of Nectria haematococca Berk, et Br. (880701 a-1) causing blight disease on ornamental plants, Phalaenopsis spp. and Doritanopsis spp. Its structure was established by spectroscopic methods. Haematocin inhibited the germ-tube elongation and spore-germination of Pyricularia oryzae at the ED₅₀ values of 30μg/ml and 160μg/ml, respectively.

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