Abstract
A 66-year-old man was admitted to our hospital with abdominal pain. Conservative treatment was administered according to a diagnosis of acute aggravation of chronic pancreatitis. In response to continued hyper-cancer antigen (CA)19-9 hematopoiesis, we performed a computed tomography (CT) and found a tumor showing contrast enhancement in the duodenal bulb. Esophagogastroduodenoscopy (EGD) showed that the tumor exceeded 10 mm in size ; therefore, distal gastrectomy (D2) and partial duodenectomy were performed. There was no lymph node metastasis upon postoperative pathological examination. Tumor diameter, invasion depth, and presence or absence of mitotic images are important factors for predicting metastatic risk in duodenal neuroendocrine tumors ; however, the optimal treatment strategy and operative techniques remain unknown.