New Dithiolopyrrolone Antibiotics from Saccharothrix sp. SA 233 II. Physicochemical Properties and Structure Elucidation

LYNDA LAMARI; ABDELGHANI ZITOUNI; TAHAR DOB; NASSERDINE SABAOU; AHMED LEBRIHI; PIERRE GERMAIN; ELISABETH SEGUIN; FRANÇOIS TILLEQUIN

doi:10.7164/antibiotics.55.702

New Dithiolopyrrolone Antibiotics from Saccharothrix sp. SA 233

II. Physicochemical Properties and Structure Elucidation

LYNDA LAMARI, ABDELGHANI ZITOUNI, TAHAR DOB, NASSERDINE SABAOU, AHMED LEBRIHI, PIERRE GERMAIN, ELISABETH SEGUIN, FRANÇOIS TILLEQUIN

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JOURNAL FREE ACCESS

2002 Volume 55 Issue 8 Pages 702-706

DOI https://doi.org/10.7164/antibiotics.55.702

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Abstract

Three new natural dithiopyrrolone antibiotics, 3-methyl-2-butenoylpyrrothine (1), tigloylpyrrothine (2), and n-butyropyrrothine (3) were isolated along with the known iso-butyropyrrothine (4) and thiolutin (5) from the fermentation broth of Saccharothrix sp. SA 233. The structures of the novel compounds were established on the basis on their spectral data.

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