Novel Antifungal Diketopiperazine from Marine Fungus

HEE-GUK BYUN; HUIPING ZHANG; MASAMI MOCHIZUKI; KYOKO ADACHI; YOSHIKAZU SHIZURI; WON-JAE LEE; SE-KWON KIM

doi:10.7164/antibiotics.56.102

HEE-GUK BYUN, HUIPING ZHANG, MASAMI MOCHIZUKI, KYOKO ADACHI, YOSHIKAZU SHIZURI, WON-JAE LEE, SE-KWON KIM

著者情報

ジャーナルフリー

2003 年 56 巻 2 号 p. 102-106

DOI https://doi.org/10.7164/antibiotics.56.102

詳細

抄録

Marine fungi producing antifungal compounds were screened against Pyricularia oryzae (P. oryzae), and a metabolite of marine fungus M-3 isolated from laver (Porphyra yezoensis) showed potent activity. Novel diketopiperazine (1) was isolated from the culture extracts, and its structure was elucidated by spectroscopic methods. The MIC of 1 against P. oryzae was 0.36μM.

責任著者(Corresponding author)

J-STAGEへの登録はこちら（無料）