Enniatin Production by the Entomopathogenic Fungus Verticillium hemipterigenum BCC 1449

SUMALEE SUPOTHINA; MASAHIKO ISAKA; KANYAWIM KIRTIKARA; MORAKOT TANTICHAROEN; YODHATHAI THEBTARANONTH

doi:10.7164/antibiotics.57.732

Enniatin Production by the Entomopathogenic Fungus Verticillium hemipterigenum BCC 1449

SUMALEE SUPOTHINA, MASAHIKO ISAKA, KANYAWIM KIRTIKARA, MORAKOT TANTICHAROEN, YODHATHAI THEBTARANONTH

著者情報

ジャーナルフリー

2004 年 57 巻 11 号 p. 732-738

DOI https://doi.org/10.7164/antibiotics.57.732

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抄録

Optimal fermentation conditions for enniatin production using the entomopathogenic fungus Verticillium hemipterigenum BCC 1449 have been investigated. Among various liquid media tested, highest efficiency of enniatin production was achieved by fermentation in yeast extract sucrose. Application of this condition to large-scale fermentation resulted in the isolation of three new analogs, O₁, O₂ and O₃, which are closely related isomers that were characterized as an inseparable mixture, along with seven known enniatins.

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