Abstract
The drug activity of rifampicin (RFP) and capreomycin (CPM), viomycin (VM) or kanamycin (KM) against Mycobacterium tuberculosis was examined in vitro. Thirty strains tested were isolated from the in-patients with pulmonary tuberculosis. KIRCHNER agar containing 10% albumin was used for the examination.
(1) The strains resistant to 100 mcg/ml of CPM, VM or KM were susceptible to RFP, and the strains resistant to 100 mcg/ml of RFP were also susceptible to CPM, VM or KM.
(2) Therefore, in the strains isolated from the patients, no cross resistance between RFP and CPM, VM or KM was observed.