The Japanese Journal of Antibiotics
Online ISSN : 2186-5477
Print ISSN : 0368-2781
ISSN-L : 0368-2781
DRUG ACTIVITY OF RIFAMPICIN AND CAPREOMYCIN, VIOMYCIN, OR KANAMYCIN AGAINST MYCOBACTERIUM TUBERCULOSIS ISOLATED FROM PULMONARY TUBERCULOUS IN-PATIENTS
KOICHI ENDO
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1970 Volume 23 Issue 4 Pages 387-389

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Abstract
The drug activity of rifampicin (RFP) and capreomycin (CPM), viomycin (VM) or kanamycin (KM) against Mycobacterium tuberculosis was examined in vitro. Thirty strains tested were isolated from the in-patients with pulmonary tuberculosis. KIRCHNER agar containing 10% albumin was used for the examination.
(1) The strains resistant to 100 mcg/ml of CPM, VM or KM were susceptible to RFP, and the strains resistant to 100 mcg/ml of RFP were also susceptible to CPM, VM or KM.
(2) Therefore, in the strains isolated from the patients, no cross resistance between RFP and CPM, VM or KM was observed.
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© Japan Antibiotics Research Association
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