Abstract
We report here the results of clinical application of lividomycin (LVM) for treating various urinary tract infections, as well as some fundamental investigations.
The blood level peak of LVM intramuscularly administered in a single dose of 0.5g appeared after one hour and then decreased rapidly. The effective blood level remained for 6 hours.
The antimicrobial activity of LVM against Pseudomonas and E. coli was considerably high.
LVM was effective in 53.1% of a series of 32 cases of urinary tract infections, i.e., markedly effective in 11, and moderately effective in 6 cases, and ineffective in the remaining 15 cases.
In spite of our special attention to nervous disturbances such as impaired hearing, dizziness and tinnitus, noteworthy side effects were not found.
