Abstract
The following results were obtained from oral administration of amoxicillin to 20 cases of acute otorhinolaryngological infections for 5 consecutive days; the daily dose was 1,500mg for adult and 750 mg for child.
1) Six cases with acute tonsillitis, 6 with acute pharyngolaryngitis, 5 with acute otitis media, 2 with furuncle of the nose and 1 with acute laryngitis were treated with amoxicillin. This drug was remarkably effective in 2 of 20 cases in total, effective in 15, slightly effective in 1 and non-effective in 2.
2) The sensitivity test to amoxicillin by the use of ampicillin sensitivity disk revealed that all of isolated bacteria were remarkably sensitive (+++) to amoxicillin, except one strain of Staphylococcus aureus which was moderately sensitive (++).
3) Side effect occurred at the rate of 25%; 4 cases of eruption and 1 of esophagitis. Other severe side effects were not observed. From the above results, amoxicillin is considered to be an effective drug for clinical application in the otorhinolaryngological field.
