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TADASHI FURUHATA, KEIICHIRO YAMAMOTO, YOSHIAKI KATABA
1976 Volume 29 Issue 1 Pages
1-3
Published: January 25, 1976
Released on J-STAGE: May 17, 2013
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1. Amoxicillin was used for treatment of 15 cases of infectious diseases in the surgical field and for prevention of 4 cases of postoperative infection, and good result was obtained in all 19 cases. Especially in the latter 4 cases, amoxicillin showed good preventive effect.
2. Any side effect probably due to amoxicillin was observed in no case.
3. Amoxicillin at a daily dose of 1,000mg (potency) exhibited sufficient effect in treatment of infectious diseases in the surgical field and in prevention of postoperative infection.
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HITOSHI SATO, TAKUYA MAYUZUMI
1976 Volume 29 Issue 1 Pages
4-6
Published: January 25, 1976
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Amoxicillin (AMPC), an oral preparation of broad spectrum synthetic penicillin, was used for treatment of 10 cases with urological infection, and the following results were obtained.
1) AMPC at a daily dose of 750-1,500mg was administered for 7-49 days to 5 cases of acute cystitis, 2 cases of acute epididymitis and one case each of calculous hydronephrosis, chronic prostatitis and postoperative cystitis. As the result, AMPC was found remarkably effective in 2 cases, effective in 7 cases and ineffective in one case; that is, the effective rate was 9/10 (90.0%).
2) Total 8 strains of bacteria, comprising 5 strains of Escherichia coli and one strain each of Klebsiella, Staphylococcus epidermidis and Pseudomonas, were isolated from the urine. These bacteria were relatively responsive to AMPC as well as to ABPC.
3) The side effect possibly due to AMPC was slight gastro-intestinal disorder only in 2 of 10 cases. No other side effect was observed.
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KEN NAKAYAM, SEIICHNI AKAMUTA
1976 Volume 29 Issue 1 Pages
7-10
Published: January 25, 1976
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Amoxicillin (Pacetocin Kyowa) was orally administered in a daily dose of 1g (potency) to 5 cases with urological infections and 15 cases with postoperative infections. As a result the drug was found remarkably effective in one case, effective in 15 cases and ineffective in 3 cases; in one case, the response to amoxicillin was uninterpittable. No severe side effect was observed during the treatment.
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RYOJI UMINO, YASUHIDE YAMAMOTO
1976 Volume 29 Issue 1 Pages
11-16
Published: January 25, 1976
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Seventeen cases of acute simple cystitis were treated by oral administration of amoxicillin at a daily dose of 1.0g (250 mg±4 in a day) for consecutive 7 days, and the following results were obtained.
1) Amoxicillin was remarkably effective in 11 of total 17 cases, effective in 2, slightly effective in 2 and non-effective in 2.
2) In terms of effect against isolated bacteria, amoxicillin was remarkably effective against 6 of 11 strains of E. coli, effective against 2, slightly effective against 2 and non-effective against 1, remarkably effective against 2 of 3 strains of Proteus mirabilis and non-effective against 1, and remarkably effective against one strain of Staphylococcus epidermidis.
3) There was no severe side effect specially to be mentioned.
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YASUNORI KUBO, TOSHIHIKO ONO, NORIYUKI IWAMOTO, IBUKI YAJIMA
1976 Volume 29 Issue 1 Pages
17-21
Published: January 25, 1976
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The following results were obtained from treatment of 29 cases of lower urinary tract infections with amoxicillin.
1) Amoxicillin was remarkably effective in 13 cases of acute cystitis, in terms of effect according to dose and bacterial species.
2) The effective rate of amoxicillin in 10 cases of chronic cystitis amounted only to 30% due to complications and resistant bacteria.(The group given 1,500mg/day was a little higher in the effective rate than the 750 mg/day group.)
3) Amoxicillin was low in effect against infections with Pseudomonas aeruginosa and hardly effective against bacteria resistant to amoxicillin.
4) So far as this study is concerned, amoxicillin produced good clinical results at a half dose of ampicillin, as in the fundamental experiment.
5) Any severe side effect was observed in no case.
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KEN OKAMOTO, AKIO YOSHIDA, AI KONA, MASAO IKEDA, JUNKO MURAOKA, IKUKO ...
1976 Volume 29 Issue 1 Pages
22-26
Published: January 25, 1976
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The following results were obtained from oral administration of amoxicillin to 20 cases of acute otorhinolaryngological infections for 5 consecutive days; the daily dose was 1,500mg for adult and 750 mg for child.
1) Six cases with acute tonsillitis, 6 with acute pharyngolaryngitis, 5 with acute otitis media, 2 with furuncle of the nose and 1 with acute laryngitis were treated with amoxicillin. This drug was remarkably effective in 2 of 20 cases in total, effective in 15, slightly effective in 1 and non-effective in 2.
2) The sensitivity test to amoxicillin by the use of ampicillin sensitivity disk revealed that all of isolated bacteria were remarkably sensitive (+++) to amoxicillin, except one strain of Staphylococcus aureus which was moderately sensitive (++).
3) Side effect occurred at the rate of 25%; 4 cases of eruption and 1 of esophagitis. Other severe side effects were not observed. From the above results, amoxicillin is considered to be an effective drug for clinical application in the otorhinolaryngological field.
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YOSHIAKI SO, AKIRA DOI, NORIKO OHSATO, MOTOI OGUCHI
1976 Volume 29 Issue 1 Pages
27-29
Published: January 25, 1976
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The following are the clinical results of amoxicillin used for 21 cases of purulent dermatoses.
Amoxicillin was remarkably effective in 5 of total 21 cases, effective in 12, slightly effective in 2 and non-effective in 2; that is, amoxicillin produced good results.
One case each of drug eruption and abdominal distention were observed as side effects.
Judging from its level in the blood, amoxicillin is expected to exhibit good therapeutical effect at a daily dose of 750-1,000mg. Amoxicillin can be considered to be an effective drug for purulent dermatoses without severe side effect.
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HISAKO TAMAKI, YUKAKO KINOSHITA, KYOKO TANABE, HIDEAKI YOGI, GOUEN INO ...
1976 Volume 29 Issue 1 Pages
30-35
Published: January 25, 1976
Released on J-STAGE: May 17, 2013
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TAKASHI NAKAMURA, IKUO HASHIMOTO, YASUO SAWADA
1976 Volume 29 Issue 1 Pages
36-42
Published: January 25, 1976
Released on J-STAGE: May 17, 2013
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IWAO UMEZAWA, HIROKO OGAWA, KANKI KOMIYAMA, YASUAKI KAWAKUBO, TOYOHIKO ...
1976 Volume 29 Issue 1 Pages
43-54
Published: January 25, 1976
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IWAO UMEZAWA, HIROKO OGAWA, KANKI KOMIYAMA, YASUAKI KAWAKUBO, TOYOHIKO ...
1976 Volume 29 Issue 1 Pages
55-60
Published: January 25, 1976
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MEIKI MATSUZAKI, NOBUE TADO, YOKO HIRATA, MAKOTO KATO, KOICHI NAKAMURA ...
1976 Volume 29 Issue 1 Pages
61-68
Published: January 25, 1976
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MEIKI MATSUZAKI, KOICHI NAKAMURA, YOKO HIRATA, HIROYOSHI MATSUMOTO, KE ...
1976 Volume 29 Issue 1 Pages
69-76
Published: January 25, 1976
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MEIKI MATSUZAKI, KUNIKATSU ONODERA, YOKO HIRATA, HIROYOSHI MATSUMOTO, ...
1976 Volume 29 Issue 1 Pages
77-82
Published: January 25, 1976
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MEIKI MATSUZAKI, HIROYOSHI MATSUMOTO, KENSUKE OCHIAI, YOKO HIRATA, MIS ...
1976 Volume 29 Issue 1 Pages
83-89
Published: January 25, 1976
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MEIKI MATSUZAKI, MASAKATSU OHTAWA, ISAMU AKIYAMA, MICHIYO YAMAMATO, JU ...
1976 Volume 29 Issue 1 Pages
90-106
Published: January 25, 1976
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MEIKI MATSUZAKI, KUNIKATSU ONODERA, ISAO OKAZAKI, AKIRA NAKAJIMA, KATS ...
1976 Volume 29 Issue 1 Pages
107-121
Published: January 25, 1976
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MEIKI MATSUZAKI, TOSHIO KAMEI, YUKIKO FURUTANI, SADAO AKUTSU
1976 Volume 29 Issue 1 Pages
122-128
Published: January 25, 1976
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MEIKI MATSUZAKI, SADAO AKUTSU, HIDEO MUKOGAWA, TATSUO SHIMAMURA
1976 Volume 29 Issue 1 Pages
129-143
Published: January 25, 1976
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MEIKI MATSUZAKI, SADAO AKUTSU, HIDEO MUKOGAWA, KOZUE KOBAYASHI
1976 Volume 29 Issue 1 Pages
144-152
Published: January 25, 1976
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