Abstract
Oral sustained release cephalexin (S-6437) was administered to 24 pediatric patients. Daily dose used was 18-60mg/kg, which was divided into two doses and given after breakfast and dinner. The following are the results of the study.
Out of 24 patients, 6 showed very good response, 10 good response, 6 fair, 1 poor and 1 unknown, Ratio of effectiveness was 69.6%.
Two patients were reluctant to receive the drug and, therefore, they took other drugs. The other 22 patients, however, were easily given.
No remarkable side effects due to S-6437 were found.
From the above results, it was recognized that S-6437 has good effectiveness and safety, and that it is convenient to give to children because the frequency of the drug administration is only twice a day.
