Abstract
A female adult suffering from fish tape-worm infection was successfully treated with a single oral administration of 4,000mg aminosidine, a paromomycin.
The drug concentration in the segments of the worm removed were as high as 600mg/ml or more, meanwhile, serum level and urinary recovery in the patient were very low.
Consequently, it was presumed that some acute effect, such as neuro-muscular toxicity, of the drug, which was well absorbed into parasite, but ill-absorbed from the gastrointestinal tract of human, is one of the mode of antihelminthic activity, in this case.
