1981 Volume 34 Issue 12 Pages 1691-1696
In order to evaluate effectiveness of cefroxadine (CXD) in the treatment of bacterial infections of children, the clinical studies were carried out.
CXD was orally administered to 30 patients at daily dose of 27.5-50.0mg/kg (average 32.3mg/kg) in 3-4 divided dose for 3-10 days (average 4.9 days).
The overall efficacy rate in30cases was 93.3%, i.e., excellent in 22 (73.3%), good in 6 (20.0%), fair in 1 (3.3%) and poor in 1 case (3.3%).
Drug eruption and transient eosinophilia were observed in 1 case each out of 30 cases (6.7%), but any other abnormality was not observed throughout this series.
Based on the above results, CXD was thus considered to be a useful antibiotic in treatment of pediatric infections.
