Abstract
The subacute toxicity of netilmicin (NTL), an aminoglycoside antibiotic, in Beagle dogs was compared with that of gentamicin (GM).NTL at dose levels of1.5, 6, 25and100mg/kg/day and GM at dose levels of6and 25mg/kg/day were given intramuscularly for30 days.Control dogs received physiological saline.After the termination of the administration period, 2 males and 2 females among 5 males and 5 females from each group* were retained for a30-day recovery period. (For the GM 25mg/kg/day group, 1male and1female were retained for the recovery test)