The Japanese Journal of Antibiotics
Online ISSN : 2186-5477
Print ISSN : 0368-2781
ISSN-L : 0368-2781
THIRTY-DAY SUBACUTE INTRAMUSCULAR TOXICITY STUDY AND THIRTY-DAY RECOVERY STUDY OF NETILMICIN IN BEAGLE DOGS
MASAO NAKAZAWATOMONOBU TOKIWAAKIRA NOMURAKOJI MIYOSHINAOKI SENOTOMOKO HONDA
Author information
JOURNAL FREE ACCESS

1982 Volume 35 Issue 2 Pages 525-613

Details
Abstract
The subacute toxicity of netilmicin (NTL), an aminoglycoside antibiotic, in Beagle dogs was compared with that of gentamicin (GM).NTL at dose levels of1.5, 6, 25and100mg/kg/day and GM at dose levels of6and 25mg/kg/day were given intramuscularly for30 days.Control dogs received physiological saline.After the termination of the administration period, 2 males and 2 females among 5 males and 5 females from each group* were retained for a30-day recovery period. (For the GM 25mg/kg/day group, 1male and1female were retained for the recovery test)
Content from these authors
© Japan Antibiotics Research Association
Previous article Next article
feedback
Top