The Japanese Journal of Antibiotics
Online ISSN : 2186-5477
Print ISSN : 0368-2781
ISSN-L : 0368-2781
CLINICAL STUDY ON CEFOTIAM OF INFECTIOUS DISEASES IN THE OTORHINOLARYNOOLOGICAL FIELD
FUMIHIKO SATO, MASAYOSHI TACHIBANA, HITOSHI SAITO, OSAMU MIZUKOSHI, TAKESHIGE NISHIMURA, AKIRA SAITO, AKIMASA NAKAMURA, KAZUHARU OKAWA, SATORU TAKENOUCHI, KUNIO YANOHARA, FUMIKAZU MIZUKOSHI, HIDEKI MATSUOKA
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1983 Volume 36 Issue 10 Pages 2688-2692

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Abstract
Cefotiam (CTM) was intravenously given to 12 patients with infectious diseases in the field of otorhinolaryngology including 10 cases with chronic suppurative otitis media. Daily doses of CTM were 1 to 4g.Clinical responses were excellent in 3 patients, good in 5, fair in 1 and poor in 3.The rate of overall clinical effectiveness was 67%.Staphylococcus species were most frequently isolated from the patients and all of them were eradicated by the CTM treatment.No side effects and no abnormal laboratory findings relating to the drug administration were observed.
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The Journal of Antibiotics, Series B

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