CLINICAL STUDIES ON COMBINATION THERAPY OF CEPHEM ANTIBIOTICS IN CHRONIC COMPLICATED URINARY TRACT POLYMICROBIAL INFECTIONS DUE TO PSEUDOMONAS AERUGINOSA AND OTHER RACTERIA
1984 Volume 37 Issue 9 Pages 1669-1678
Details
1984 Volume 37 Issue 9 Pages 1669-1678
Patients with chronic complicated urinary tract polymicrobial infections due to Pseudomonas aeruginosa and other bacteria were treated with cefsulodin using cefotiam or cefmenoxime as a concomitant drug. Each drug was given to the patients in daily dose of 1 or 2 g by drip infusion twice a day for 5 to 16 days. The results were as follows.
1. Overall clinical efficacy was excellent in 7 cases (44%), moderate in 6 cases (38%) and poor in 3 cases (19%), the effectiveness rate being 81.3%.
2. Bacteriologically, 38 strains (88.4%) were eradicated, 1 strain decreased and 4 strains unchanged out of the 43 clinical isolates from the patients.
3. No side effects and no abnormalities of laboratory findings were observed.
