1984 Volume 37 Issue 9 Pages 1679-1684
Cefoxitin (CFX) was administered to 12 patients with respiratory tract infections, including mainly patients with pulmonary suppuration or pyothorax. The results were as follows:
1. CFX was effective in 75% of the total patients, and in 83% of the 6 patients with pulmonary suppuration or pyothorax.
2. Microorganisms which were considered to be causative were isolated in 8 of 12 patients. Bacterio-logical responses were “eradicated” in 4 patients, “replaced” in 3 patients, “unchanged” in 1 patient.
3. A slight elevation of S-GPT was observed in one patient and elevation of A1-P in another following CFX administration; however, these values returned to normal shortly after completion of drug administration. No adverse effects, allergic symptoms or laboratory abnormalities were observed.