The Japanese Journal of Antibiotics
Online ISSN : 2186-5477
Print ISSN : 0368-2781
ISSN-L : 0368-2781
FLUCONAZOLE TREATMENT FOR SYSTEMIC MYCOSES
TAKESHI MORI, MAKIKO MATSUMURA, TSUKASA EBE, MAYUMI TAKAHASHI, TOMOO KOHARA, MASAYOSHI INAGAKI, HIROSHI ISONUMA, ICHIROU HIBIYA, TSUNEO HAMAMOTO, KAZUYOSHI WATANABE, HIDEO IKEMOTO, MARI KUROKAWA
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1989 Volume 42 Issue 1 Pages 55-62

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Abstract
Efficacies of fluconazole, a new triazole antifungal agent, were evaluated in 11 cases of systemic mycoses (1 case each of candiduria, pulmonary cryptococcosis, pulmonary aspergillosis, pulmonary penicilliosis and suspected fungal pulmonary infection, and 3 cases each of candidemia and Candida endophthalmitis).
The clinical efficacies were excellent or good in 8 out of 9 cases and poor in 1.
Side effects observed were mild with 1 incident each of gastrointestinal symptom and reversible leukopenia.
This drug appears to be promising in treatment of systemic mycoses.
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© Japan Antibiotics Research Association
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The Journal of Antibiotics, Series B

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