The Journal of Antibiotics, Series A
Online ISSN : 2435-5135
Print ISSN : 0368-1173
ISSN-L : 0368-1173
Original Articles
Experimental Study on the Oncostatic Activity of Actinomycin J. I Histological Findings of Therapeutic Effects on Ehrlich’s Mouse Ascites Carcinoma in the ddN Strain Mice
Kunio OotaAtsushi NishiboriNoboru Takahashi
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1957 Volume 10 Issue 2 Pages 46-55

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Abstract

One of the present authors has reported inhibitory action of sarkomycin on Ehrlich’s ascites carcinoma ionculated to the mice of ddN strain in the 6th week of life. A natural history and histological sequence of growth of Ehrlich’s mouse carcinoma after intraperitoneal inoculation to the particular mouse strain were well established in the above study.

The present paper reports some data from a similar series of experiments using Actinomycin J. Irrespective of the younger age of the animals used and slight difference of season, the control groups showed almost exact repetition of the natural history.

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© 1957 JAPAN ANTIBIOTICS RESEARCH ASSOCIATION
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