Biological Studies on Antifungal Substances Produced by Streptomyces Fungicidicus

Abstract

As reported in a previous paper¹⁾, two antifungal substances were isolated from a culture filtrate of S. fungicidicus. The one, unamycin, was a tetraene antifungal substance and another, unamycin B, was an antifungal substance related to toyokamycin²⁾ and the antibiotic E-212³⁾. Processes for production and isolation and properties of these antifungal substances were described in the previous paper. Antifungal effects, and toxicities are presented in this paper.