Pathocidin, A New Antifungal Antibiotic. II Taxonomic Studies on the Pathocidin-Producing Organism Streptomyces Albus var. Pathocidicus

Abstract

In order to discover antibiotics for agricultural chemicals, we have isolated actinomycetes from the soil, and discovered Streptomyces sp. B-28 which produces 2 antibiotics effective against Pricularia oryzae in vitro and in the greenhouse test. The one was proved to be identical with blastcidin S discovered by S. Takeuchi et al.¹⁾, and the other was named pathocidin²⁾. Pathocidin was found to be identical with 8-azaguanine as reported by Anzai, et al.³⁾, which is effective on Penicillium, Aspergillus and various phytopathogenic fungi.

In this report, the bacteriological characteristics of pathocidin-producing organism are described, and it was named Streptomyces albus var. pathocidicus.