A Streptomyces Producing O-Carbamyl-D-Serine

抄録

Culture filtrates of actinomycetes were screened for the activity of selectively inhibiting growth of B. subtilis and its mutant requiring adenine, cytosine and uracil. A culture filtrate was found to inhibit growth of B. subtilis more strongly than the mutant in certain synthetic medium. The active substance was isolated and confirmed to be o-carbamyl-d-serine. The isolation of this substance from a streptomyces had been reported by Hagemann, Pennasse and Teillon¹⁾, but these authors did not describe characters of the streptomyces. Characters of the streptomyces which was isolated by the present authors and which produced o-carbamyl-d-serine, processes for the isolation and some biological activities of this substance are presented in this paper.