Archivum histologicum japonicum
Print ISSN : 0004-0681
肝細胞脂質の組織学的研究
III. 自律神經毒による影響
堀田 卓
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ジャーナル フリー

1952 年 3 巻 2 号 p. 229-231

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E. ABDERHALDEN has expatiated on the intimate relation existing between the metabolism of fatty substances in the liver and the functions of hormones and the autonomic nervous system. However, this problem has as yet, many indistinct questions to be clarified. After subcutaneous injections of autonomic nerve poisons, namely, 1mg adrenalin, 0.5mg pilocarpin, and 1mg atropin per kg body weight, respectively, into hungry rats, the author has histologically studied the fat in liver cells and has obtained the following data.
1. After injections of the poisons, the fatty substances in liver cells increased and thereafter decreased.
2. The effects of adrenalin were similar to those of atropin, but those of pilocarpin were somewhat slacker.
All these medicaments raise the basal metabolism and induce fatty substances to appear in liver cells. It is to be taken into consideration that in the case of adrenalin the sympathetic, and in the case of pilocarpin the parasympathetic nervous system is excited, whereas atropin paralyses the latter
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