The Clinical Investigation of the Bronchial Asthma Caused by the Pollen of Nerium Indicum : 1st Report. Nerium pollen Allergen Extract

Abstract

The clinical investigation of the Bronchial Asthma caused by the pollen of Nerium indicum Mill, which is distributed widely in west Japan, is described. The pollination of the tree of Nerium is from June to October in Amagasaki district. The results are as follows. 1. Among 61 cases of Bronchial Asthma, who visited my allergic clinic in this autumn, 16 cases of the pollen asthma of Nerium were demonstrated, the intradermal test with Nerium pollen extract. 2. Of these 16 cases of Nerium Pollen Asthma, 3 cases were negative to the intradermal test with other allergen extract. 3. By the anamnesis, these 16 cases of Nerium Pollen Asthma were sick enough during the pollination of Nerium indicum, mostly in June, July, August and September. 4. Most of the patients with Nerium Pollen Asthma are living in the suberb of Amagasaki city where preater part of the tree is planted. 5. When P-K reaction with the pollen extract of Nerium was examined for 2 cases of these Nerium Pollen Asthma, one was positive and the threshold of the reaction was 1 : 2^3.