Annals of Vascular Diseases
Online ISSN : 1881-6428
Print ISSN : 1881-641X
ISSN-L : 1881-641X
Series: Lymphology from the Journal of Japanese College of Angiology
Mucosal Immunity in Gut and Lymphoid Cell Trafficking
Soichiro MiuraRyota HokariYoshikazu Tsuzuki
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2012 Volume 5 Issue 3 Pages 275-281


Intestine has a well-developed lymphatic system that is closely related with its functions, such as mucosal immunological defense or absorption of nutrients. Intestinal lymphoid cells such as lymphocytes, macrophages/monocytes, or dendritic cells are continuously migrating through intestinal mucosa, thereby facilitating their immune responses. Their migrations are well controlled by well-organized molecular mechanisms including adhesion molecules, chemokines, etc. This manuscript will review how dysfunction of lymphoid cell migration is involved in intestinal inflammation, especially in the pathophysiology of intestinal bowel diseases. (*English Translation of J Jpn Coll Angiol 2008; 48: 143-149.)

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この記事はクリエイティブ・コモンズ [表示 - 非営利 - 継承 4.0 国際]ライセンスの下に提供されています。
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