1996 Volume 60 Issue 8 Pages 1372-1374
Sporogen AO-1 is a sporulation-stimulating substance isolated from Aspergillus oryzae. We speculated that ring B would be important for the activity and designed a compound without functional groups in ring A. We synthesized the compound from 2-methylcyclohexanone via chiral octalone. The compound showed activity at 200 μg/disc. The functional groups on ring B are suggested to be important for the activity.
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