1991 Volume 10 Issue 1 Pages 53-64
Effects of a high cholesterol (HC) diet and HC diet supplemented with polydextrose on fecal flora, fecal bacterial enzyme activity and fecal putrefactive products in eight healthy volunteers were studied. They were fed a low cholesterol (LC) diet, HC diet, HC diet supplemented with polydextrose (15 g/day) (HCP) at 2-week intervals consecutively for 6 weeks. Polydextrose supplementation increased fecal weight and decreased fecal pH and the stool concentration of indole, p-cresol, iso-valeric acid and iso-butyric acid. A significant reduction of Clostridium in the feces was also observed during the HCP diet period. The frequency of occurrence and number of Clostridium perfringens in the feces were lower for the HCP diet than for the HC diet.