Abstract
The resistance of bifidobacteria to six kinds of antibiotics was examined. Bifidobacteria were isolated from the feces of healthy individuals (12 cases) and patients (11 cases) administered an antibiotic-resistant Bifidobacterium preparation (LacBR ®). These patients were given antibiotic drugs etc. Only a few of the healthy individuals had the bifidobacteria resistant to ampicillin, cefazolin, erythromycin, minocycline and ofloxacin. However, many of the LacB-R ®-administered individuals had the bifidobacteria resistant to the antibiotics except minocycline and ofloxacin. All persons in both group showed resistance to amikacin. The administration of LacBR ® was useful to maintain the number of intestinal Bifidobacterium because administered Bifidobacterium was recovered with the healthy control level in some of the patients receiving therapy with many kinds of antibiotics.
