Abstract
Helicobacter pylori shows a highly diverse nature in all aspects, from gene profiles to biological features. between H. pylori and host cells is also complex. These characteristics of H. pylori may explain some conflicting results regarding the pathogenicity of H. pylori in human diseases. Not all strains are pathogenic, as exemplified by Type I and Type II strains. This may possibly lead to the development of a live vaccine using non-toxic strains against toxic strains. To achieve this goal, further study is necessary to elucidate the exact role of H. pylori in gastroduodenal diseases.
