Bioscience and Microflora
Online ISSN : 1349-8355
Print ISSN : 1342-1441
ISSN-L : 1342-1441
In-Vivo Selection of a Strain of Bifidobacterium with a High Potential to Colonise the Gastrointestinal Tract of Mice and Studying Its In-Vitro Characteristics
Azra PACHENARIPatricia L. CONWAYMartin J. PLAYNE
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2002 Volume 21 Issue 2 Pages 107-114

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Abstract

The potential of six strains of Bifidobacterium to colonise the gastrointestinal (GI) tract of Swiss mice, their interaction i n the GI tract of Swiss mice and their in-vitro characteristics were investigated. This study revealed that a strain of Bifidobacterium that was isolated from a C57BL/10 ScSn mouse was capable of colonising the GI tract of Swiss mice and remaining there for at least one month. The in-vitro studies showed that this strain had the highest capability among the six strains to adhere to the intestinal tissue of BALB/c mice. This strain grew in presence of 2% bile and lost less than 10-fold viability at pH 2.5.

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