Biocontrol Science
Online ISSN : 1884-0205
Print ISSN : 1342-4815
ISSN-L : 1342-4815
Development of a Method to Reduce Microbial Numbers in Powdered Crude Drugs by a Copper-Alcohol Treatment
YOSHIKAZU SAKAGAMIKATSUHIRO YAMASAKI
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2003 年 8 巻 3 号 p. 119-122

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The effectiveness of a copper-alcohol treatment to reduce the microbial numbers in the powdered crude drugs was investigated. Furthermore, the effect on the chemical quality control was also evaluated. After the treatment, no microorganisms and no changes in the appearance of the crude drugs were found. Furthermore, no remarkable change in the contents of index components in the powdered crude drugs was found except for that of swertiamarin and gentiopicroside in gentian and that of ginsenoside Rb1 and Rg1 in ginseng. These results suggest that this treatment method would be very useful to reduce the number of microorganisms in powdered crude drugs.
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© The Society for Antibacterial and Antifungal Agents, Japan
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