1. In the course of the disintegration of hexosediphosphoric acid to lactic acid by a series of enzyme systems which are contained in autolyzed liver, the accelerating effect of reduced glutathione operated only on glyoxalase. Other enzyme were unaffected. 2. The inhibitory action of monoiodoacetic acid was also restricted to glyoxalase only. The acid reacted with the co-enzyme reduced glutathione, but not with glyoxalase itself.
