抄録
Upon the fate of glucosamine administered to normal rabbits, the following points were noticed.
1. Gly cogenesis was observed, but to a less extent than when the amount of glucose equivalent to glucosamine was given.
2.The glucosamine is secreted partially into urine. Ammonia-and urea-nitrogen increased also in urine but the sum of the increments of ammonia-, urea- and aminosugarnitrogen did not reach the amount of the total extranitrogen. No reducing substance except glucosamine was eliminated in urine under the experimental conditions adopted.
3. Lactic acid was secreted into urine, when glucosamine was administered, but not at all when equivalent glucose was applied, though lactic acid content of blood is the same in both sugars.
4. pH of urine decreases even when glucosamine chlorhydrate was given after being neutralized.
5. Fructosazine was not detected in urine.
Sincere thanks are due to Professor K. Kodama for criticism and advice; to Dr. M. Mita, Professor of Pediatry, for encouragement, and particularly to Assistant Professor H. Masamune for kind direction and continuous encouragement throughout this work.
