抄録
1. Fishes are quite suitable test subjects for the biological action of many soluble and diffusible substances.
2. Easily permeable substance like saponin, adrenalin and atropin can be promptly absorbed, especially through the gills and effect their specific action.
3. Insulin can act through the gill. Perhaps it consists of easily dialysable and non dialysable fraction.
4. Urease seems to be impermeable to the gills. The partial trypsin digestion makes urease more permeable and accordingly becomes active when applied through the gills. On the prolonged trypsic digestion the urease action disappears entirely. The activity of urease is likely concerned with some chemical construction of polypeptid nature, destructable by trypsin, but not with colloidal structure as protein itself.
The work has been carried out under the direction of Prof. Dr. Samuro Kakiuchi, Director of Biochemical Institute of the Tokyo Imperial University, to whom the writer wishes to express his hearty thanks for the continuous guidance, precious advices and valuable criticisms given during the course of the study and also wishes to thank sincerely Prof. Dr. Shink ishi Hatai, Director of Biological Institute of Tohoku Imperial University, who has encouraged the writer through out the study.
In this place the writer wishes to express thanks for financial aid given to “the Foundation for the Promotion of Scientific and Industrial Research in Japan.”
