The Journal of Biochemistry
Online ISSN : 1756-2651
Print ISSN : 0021-924X
A CONTRIBUTION TO THE FAT METABOLISM
The first report. Experimental studies on the influence of high-fat diet upon the fat-carbohydrate metabolism
MASAKI MIYAZAKI
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1936 年 24 巻 3 号 p. 407-422

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From the experiments on dogs the following results were obtained.
1. High-fat diet continued for several days causes a fat de-position and glycogen decrease in the liver, but this effect of high-fat diet can be paralysed by the addition of carbohydrate to the same high-fat diet.
2. High-fat diet continued for several days causes a lowering of the glycogenetic function of the liver, but this effect of high-fat diet can be paralysed by the addition of carbohydrate to the same high-fat diet.
3. High-fat diet has no special influence upon the fasting level of the blood fat.
4. Preceding high-fat diet has no special influence upon the alimentary lipemia.
5. The fat accumulating power of the liver is increased by preceding high-fat diet, but it can be paralysed by the simultaneous intake of carbohydrate.
I wish to express my gratitude to Prof. N. Kageura for suggesting this study and his guidance throughout the course of my research. My thanks are due to Dr. Y. Sendju also for his help and advice.

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© The Japanese Biochemical Society
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