STUDIES ON THE OXIDATION MECHANISM OF METHYL GROUP

抄録

Toluene was chosen as substrate in invertigation of the oxidation mechanism of the methyl group. Succesive adaptation by a strain of Pseudomonas aeruginosa, was utilized for the analysis of the oxidation process of toluene. The results showed the possibility that toluene was oxidised via benzyl alcohol, benzaldehyde and benzoic acid. The formation of the former two and pyrocatechine (from toluene) was demonstrated.
In mammalian livers, benzyl alcohol and benzoic acid were identi-fied as products of toluene oxidation.
The author wishes to thank Prof. Dr. R. Hirohata for his guidance in carrying out this work. This work was carried out partly by the aid of the Scientific Research Funds of the Ministry of Education.