抄録
It has been proved that 4-hydroxy-8-methoxy-quinoline-2-carboxylic acid, diethereal sulfate of xanthurenic acid and kynurenic acid act antagonistically to xanthurenic acid with regard to the diabetogenic activity.
For the development of this activity free OH group in the 8-position of quinoline ring is necessary.
In conclusion, we heartily thank Prof. Yashiro Kotake for his pertinent advice and encouragement, Prof. K. Kodama for his revision, and also heartily thank Prof. T. Sakan for his advice to synthesis of the compounds necessary for this experiment.
