EFFECTS OF SOME COPPER COMPLEXES UPON THE OXIDATION OF 3, 4-DIHYDROXYPHENYLALANINE AND URATE
1960 年 47 巻 6 号 p. 733-740
詳細
1960 年 47 巻 6 号 p. 733-740
1. Acidic ionization constants of some unsaturated amines were determined in 70 per cent dioxane solution. The order of pK values was as follows neocuproin>o-phenanthroline>bathocuproin>2, 9-diphenyl-4, 7-dimethyl-phen-anthroline (PMP)>bathophenanthroline>dipyridyl>diquinolyl.
2. The acceleratory effect of cupric ions upon the oxidation of DOPA was activated when some unsaturated amines were added. When the mixing ratio of copper to amines was 1:1, the order of the activity coincided with that of their pK values. Beyond this ratio, some of them decreased more or less in activity while some enhanced further the catalytic activity of the cupric ions.
3. The catalytic power of cupric ions upon the oxidation of urate was. also activated if some amines were added. The order of the activity was as follows: 1) o-phenanthroline>bathophenanthroline, 2) neocuproin>batho-cuproin>PMP, 3) dipyridyl>diquinolyl. These orders in each group coincide with those of their pK values. Discussions were made concerning the catalytic activity of the amines referring to their steric configurations.
The author is greatly indebted to Prof. Adrien AIbert of the Australian National University who has read the manuscript and made valuable comments on it.
