The Journal of Biochemistry
Online ISSN : 1756-2651
Print ISSN : 0021-924X
STUDIES ON THE METHYLATION OF PYRIDINE-COMPOUND IN ANIMAL-ORGANISMS
V. COMPARISON WITH THE BEHAVIOUR OF NICOTINIC ACID IN SOME VERTEBRATE ANIMALS
YOSHIO OKUDA
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ジャーナル フリー

1960 年 48 巻 1 号 p. 13-17

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抄録
1. An attempt has been made to compare the behaviours of nicotinic acid in rabbit, domestic fowl, tortoise and frog by the chromatographic techniques.
2. The rabbit, fowl, tortoise, and frog converts nicotinic acid into nicotinamide, which is partly methylated into N1-methylnicotinamide in rabbit, tortoise, and frog except fowl showing quantitative difference and other part of it is oxidized to N1-methyl-6-pyridone-3-carboxamide in rabbit.
3. In fowl, nicotinic acid seems to be conjugated with ornithine into nicotinoyl-ornithine-like substance, while in rabbit, tortoise and frog it is conjugated with glycine.
The author wishes to express his cordial thanks to Dr. M. Tomita for his con-tinuous advice and encouragement.
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© The Japanese Biochemical Society
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