Abstract
1. Liver catalase activity of mouse was depressed progressively with time by the repeated administration of DDC, the effective doses being proportional to the body weight.
2. Repeated administration of DDC as well as AIA inhibited almost completely the recovery of the catalase activity after a single injection of AT.
3. The rate of destruction (KD) of the catalase activity lies around 0.020 with DDC, AT and AIA alike.
4. It is concluded that DDC inhibits the catalase synthesis in vivo just as AIA, although the intrisic mechanisms of inhibition may be different between them.
