Stero-bile Acids and Bile Alcohols
IXC. Fate of the 4β-Hydrogen of Cholesterol during the Biogenesis of 5α-Bile Alcohols
1967 年 61 巻 5 号 p. 633-635
詳細
1967 年 61 巻 5 号 p. 633-635
The fate of tritium during the conversion of 4β-3H-4-14C-cholesterol to 5α-bile alcohols in the carp was investigated. The labeled 5a-cyprinol and 27-deoxy-5α-cyprinol isolated from the gall bladder bile had lost most of the administered tritium. This result indicates that the reduc-tion of the double bond of cholesterol takes place after its isomerization from the Δ5 to the Δ4 position.
