The Journal of Biochemistry
Online ISSN : 1756-2651
Print ISSN : 0021-924X
Effect of Glucose and Adenosine 3', 5'-Cyclic Monophosphate on the Early Development of Dictyostelium discoideum
Keiko O. YANAGISAWAYoshimasa TANAKAKaichiro YANAGISAWA
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1974 年 75 巻 6 号 p. 1321-1325

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The effects of glucose and cAMP on the aggregation of D. discoideum were studied. The number of aggregation centers increased and the duration of the aggregation stage was prolonged by the addition of glucose, during the initial 2hr after the deprivation of food. This effect paralleled the uptake of glucose by this organism. The number of aggregates increased drastically on addition of external cAMP as aggregation proceeded, and the uptake of cAMP by the cells decreased. The duration of the aggregation stage was also prolonged by added cAMP. The effects of glucose and cAMP on the early development of D. discoideum are discussed.

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© The Japanese Biochemical Society
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