Abstract
One of the most useful method of understanding physicochemical properties of biopolymers as a thread of life is to pull and stretch them out. In this article, the method of manipulation of biopolymers by an elongational flow field was presented. As an elongational flow field generator, an opposed jets and a four roller mill apparatuses were shown. An ability of the elongational flow field of stretching flexible polymers was demonstrated by showing the elongational behavior of DNA molecules interacting with DNA binding protein HU. Orientation of monodisperse collagen molecules was shown as a model of rigid rod-like polymer orientation in the elongational flow field.
