Seibutsu Butsuri
Online ISSN : 1347-4219
Print ISSN : 0582-4052
ISSN-L : 0582-4052
Review
Collective Behavior of Microtubule Driven by Dynein
Ken H. NAGAIYutaka SUMINOKazuhiro OIWA
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2013 Volume 53 Issue 3 Pages 149-152

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Abstract
A vortex lattice of microtubules emerges in a dynein-microtubule motility assay. To clarify the physical mechanism of this collective behavior, the trajectory of isolated microtubules and the interaction between microtubules were experimentally examined. We found that the trajectory of an isolated microtubule has a long correlation time of its curvature and microtubules interact with each other through only nematic steric interaction. We developed the mathematical model based on the experimentally confirmed characteristics and concluded that long correlation time of the motion of an isolated microtubule and high density of microtubules are the key factors for the vortex lattice emergence.
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© 2013 by THE BIOPHYSICAL SOCIETY OF JAPAN
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