FLUID3EAMS: Fluid–Fluid Interfacial Energy Driven 3D Structure Emergence in A Micropillar Scaffold and Development in Bioengineering

Abstract

This review describes our recent studies about “fluid-fluid interfacial energy driven 3D structure emergence in a micropillar scaffold (FLUID3EAMS)” and its application. The FLUID3EAMS generates a 3D droplet (or hydrogel bead) array in a micropillar scaffold by a simple phenomenon that a fluid-fluid interface passes through the scaffold. The method to realize the phenomenon will be a powerful tool for application requiring ordered or arrayed microdroplets in biophysics, biology, or tissue engineering.