Cyclic nucleotides in mechano-transduction and encoding processes.

Abstract

Various kinds of stretch-activated ion channels from plant cell to vertebrate receptor cells are reviewd, with some of their general kinetics. The sensory axon terminal in muscle spindles possess a high density of mechano-transduction channles. In the isolated and decapsulated preparation of the frog muscle spindle, cyclic nucleotides are found to play a role in the encoding mechanisms and in a feedback control of these transduction channels.