Abstract
Recently developed methods of small-angle neutron scattering for molecular biology research, in particular, nuclear spin contrast variation method will be discussed by comparison of conventional methods. The Small-Angle Neutron Scattering instrument (SANS-1) at the research reactor FRG-1 at the GKSS Research Center, Germany, has been equipped with a polarized target station for the measurement of polarized neutron scatterings, which is mainly dedicated to the use of nuclear spin contrast variation method. First experiments using SANS-I with apoferritin and deuterated large subunit of E. coli ribosomes have shown the feasibility of this method.
