Abstract
Recently the mesoderm inducing factors related with growth factors have reported exponentially in the world. Especially FGF and activin seem to be the natural inducing factors. We report here the recent works of these factors concerning with the gene expression and cell differentiation. Activin and FGF can express the several kinds of homeotic genes including Mix.1, goosecold. Xhox3, Xlim-1 etc. in the presumptive ectoderm. These mesoderm inducing factors control the gene expression and cell differentiation subsequently as like as normal development in Xenopus. The possible molecular mechanisms of signal transduction of these factors are also reported in this paper.
