INHIBITORS OF POLY (ADENSINE DIPHOSPHATE RIBOSE) POLYMERASE POTENTIATE THE ANTITUMOR ACTIVITY OF BLEOMYCIN AGAINST EHRLICH ASCITES CARCINOMA

HISAE KAWAMITSU; MASANAO MIWA; YUKO TANAKA; HIROMI SAKAMOTO; MASAAKI TERADA; AKIO HOSHI; TAKASHI SUGIMURA

doi:10.1248/bpb1978.5.900

HISAE KAWAMITSU, MASANAO MIWA, YUKO TANAKA, HIROMI SAKAMOTO, MASAAKI TERADA, AKIO HOSHI, TAKASHI SUGIMURA

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Keywords: Ehrlich ascites carcinoma

JOURNAL FREE ACCESS

1982 Volume 5 Issue 11 Pages 900-904

DOI https://doi.org/10.1248/bpb1978.5.900

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Abstract

m-Aminobenzamide and benzamide, which are potent inhibitors of poly (adenosine diphosphate ribose) polymerase and have no antitumor activity themselves, potentiated the antitumor activity of bleomycin against Ehrlich ascites carcinoma in vivo.

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